Description
Probitrust 15 is a Pre-Probiotic combination, a blend of probiotic Lactobacillus and Bifidobacterium species, the two most important genuses associated with the human intestinal tract and oral adsorbent Lactitol monohydrate. Patients with chronic disease have abnormal microbiota when compared to healthy individuals. Diet and impaired protein absorption, increased intestinal transit time, medications, and uremia may all contribute to unfavorable changes in microbiota. Probiotic is used to maintain a friendly bacterial balance for support to healthy digestion. Probiotics are used to eliminate uremic toxics in CKD patients and in patients undergoing dialysis.
Composition
- Bifidobacterium longum: 5 Billion CFU
- Lactobacillus acidophilus: 5 Billion CFU
- Streptococcus thermophilus: 5 Billion CFU
- Total Count: 15 Billion CFU
- Lactitol monohydrate USP (Prebiotic): 100 mg
Pharmacodynamics
Probitrust 15 Pre-Probiotic is a blend of probiotic Lactobacillus and Bifidobacterium species, the two most important genuses associated with the human intestinal tract and oral adsorbent Lactitol monohydrate. Each capsule supplies 15 billion active cells, otherwise called colony forming units (CFU).
- Lactobacillus acidophilus 5 billion CFU: Studies have shown that dialysis patients, who were given freeze-dried Lactobacillus acidophilus, have reduced concentration of toxins (methylamine, demethylmine, nitrosamines and several other carcinogenic amines) in the bloodstream. In addition, it also helps to prevent the growth of pathogenic bacteria in the small bowel.
- Bifidobacterium longum 5 billion CFU: These bacteria utilize various phenolic and indole metabolic toxic compounds in the colonic region as its nutrients for growth.
- Streptococcus thermophilus 5 billion CFU: This bacterium actually utilizes urea/Creatinine/uric acid as nutrients for its increased growth and survival and thus help cleanse the bloodstream of urea and uric acid.
Our extensive research provides strong evidence that the three power Probiotics help the human gastrointestinal tract function as a pseudo kidney to filter out waste products that are usually the responsibility of kidney.
Indication
Probitrust 15 is indicated in Renal Impairment for reducing the burden on impaired kidney.
Dosage and Administration
The recommended dosage of Probitrust 15 in CKD is 1-2 capsules with every meal. The dose should be adjusted to suit the requirements of the individual patients.
Adverse Side Effects
Probiotic bacteria are indigenous to the human intestinal tract and their introduction into the alimentary tract is not associated with adverse side effects or considered a risk to health. The daily recommended dose, or exceeding the recommended daily dose, may cause irritation and possibly a change in stool characteristics. Dose adjustments will resolve overuse problems.
Interactions
Probiotics used too soon after an antibiotic dosing could result in a loss of antibiotic efficacy. Follow standard pharmacy recommendations for dosing separation of probiotic and antibiotic substances. Probiotic gains in friendly bacteria populations will be reduced by antibiotic therapy. Patients should be encouraged to support and maintain probiotic populations during and after an antibiotic course.
Presentation
10 capsules packed in a strip, 5 such strips packed in a carton.
